I picked this up last night and did one run as well. I'll echo what Droigan said about the controller, and it worked way better than I expected. Quick turning, smooth movement. The only thing that took some getting used to (especially after playing borderlands the pre-sequel) was the really low altitude jumping.
Also, the squareness of the rooms really weren't noticeable, or perhaps I just didnt care since there seem to be plenty of objects, pillars, stairs, etc to maneuver around. I cleared out the first level and eventually got squished by the first boss but it was quite fun.