While the upcoming-underground-bullet-train-to-Chicago ads were everywhere in 2077, I'm worried that 'the Fallout problem' is becoming universal: In games where our choices narratively leave the world in irreconcilable states, the only way to avoid having _some_ players having made the 'wrong' choices in sequels is to just blow up the setting immediately after _all_ the endings, which ironically makes _none_ of the player's choices matter.
Beyond the 'just blow it up issue', I'm not excited about Chicago specifically - that's smack dab in the middle of NUSA turf, which _should_ limit the amount of pull corpos from / other countries have. (E.g. Eddies- Euro-dollars - shouldn't be a thing.) It's also way less believable that warlords can set up their own fiefdoms (e.g. Dogtown) in the middle of a functioning country.
It seems like it should also limit the available biomes - if you haven't looked at a map recently, Chicago doesn't have any deserts, or oil fields, or even farmland anywhere near the city proper. Unless they are going all-in on just having this be city based, with maybe a smattering of razed city chunks for things like Combat Zones.
And yeah, I expect / hope this is heavily AI based as well. The problem being that AIs have basically been portrayed as omnipotent once they get into humanity's networks, unless networking is radically different in ruined Chicago (e.g. we have to reach physical access points at a site before we can use any netrunner abilities).