Coronavirus Updates, Important Information, and Ancedotal Experience
- Thread starter a_skeleton_05
- Start date
You're probably talking about this:
COVID-19:Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism
The novel coronavirus pneumonia (COVID-19) is an infectious acute respiratory caused by the novel coronavirus. The virus is the positive-strand RNA one with high homology to bat coronavirus. The pathogenic mechanism of the new coronavirus is still unclear, which is a significant obstacle to the...
chemrxiv.org
It's a pre-print paper describing how researchers used a couple kinds of computer simulation to model possible molecular interactions with virus proteins. Importantly, not even the authors claim that this is what's actually happening in the human body. It's being spread around a lot with severe lack of context.
One doctor's rebuttal (board format keeps interpreting hyperlink as media):
medium.com/@amdahl/covid-19-debunking-the-hemoglobin-story-ce27773d1096
- 1
Sanrith Descartes
Veteran of a thousand threadban wars
- 41,488
- 107,544
Could be. I just recall it describing the virus adhering to blood cells and restricting their capacity to carry O2 which was driving the hypoxia.You're probably talking about this:
COVID-19:Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism
The novel coronavirus pneumonia (COVID-19) is an infectious acute respiratory caused by the novel coronavirus. The virus is the positive-strand RNA one with high homology to bat coronavirus. The pathogenic mechanism of the new coronavirus is still unclear, which is a significant obstacle to the...
It's a pre-print paper describing how researchers used a couple kinds of computer simulation to model possible molecular interactions with virus proteins. Importantly, not even the authors claim that this is what's actually happening in the human body. It's being spread around a lot with severe lack of context.
One doctor's rebuttal (board format keeps interpreting hyperlink as media):
medium.com/@amdahl/covid-19-debunking-the-hemoglobin-story-ce27773d1096
Sanrith Descartes
Veteran of a thousand threadban wars
- 41,488
- 107,544
Look at NY fatality percentages. NYC is running 50% higher percentage than the other big counties. Either we believe NY city population are dying 50% more often or we believe NYC reporting is bullshit because they are coding every death as Coronachan no matter what.
Occam's Razor.
Occam's Razor.
Kiroy
Marine Biologist
- 34,642
- 99,968
ditto, they even sent an email a couple days ago saying "uhh ya so you're application is just sitting in line and will be procssed eventually"
I submitted my shit about an hour after they opened their portal.
- 1
Sanrith Descartes
Veteran of a thousand threadban wars
- 41,488
- 107,544
Sanrith Descartes
Veteran of a thousand threadban wars
- 41,488
- 107,544
Not sure who you bank with but we are with M&T. Our account rep has been giving us personal feedback. We get the boilerplate emails and then we get his emails which are nicer but basically say the same thing. He isn't lying to us though. He tells us he has no idea about timeline and nor doesn anyone else right now. They converted every warm body to loan processing and gave them some basic training.
Khane
Got something right about marriage
- 19,836
- 13,353
It's Sunday and a holiday to boot. Would be great if this were a legitimate number but it is very likely not.
- 1
Sanrith Descartes
Veteran of a thousand threadban wars
- 41,488
- 107,544
You might be right, but I gotta think if you are dying of Coronachan, I'm think you don't say "I'll wait to go to the hospital until tomorrow because today is Easter Sunday ".
- 1
Hoss
Make America's Team Great Again
- 25,580
- 12,049
So (rounding) 103k cases, 7k deaths, 10k recovered. Does that mean 86k in the hospital or suffering from home? Maybe they fail to track the people who are enver hospitalized or something?
Khane
Got something right about marriage
- 19,836
- 13,353
We've had a lack of good numbers reporting for 3-4 Sundays in a row. It's not about people not getting sick, hospitalized or dying on Sundays. It's that the reporting seems to take a day off on Sundays.
- 1
Sanrith Descartes
Veteran of a thousand threadban wars
- 41,488
- 107,544
- 17,781
- 25,896
I've also heard this.
If (if) it is true, then that would explain why Ventilators are not saving lives as was previously expected.
Ventilation is the mechanical movement of air in and out of the lungs. Respiration is the molecular gas-exchange that happens once that air is in the lungs, and it also happens at the level of each individual cell. Each cell 'Respirates' individually as it interacts with the bloodstream.
Hemoglobin are the Red Blood Cells and their job is to carry oxygen from the lungs to the outer tissues, and then pick up waste carbon dioxide from the tissues and deliver them to the lungs so that the lungs can then exhale that carbon dioxide as waste molecules. So then if COVID is attacking the hemoglobin in the blood, then that would mean that it is negatively impacting Respiration both at the level of the Lungs and at the level of the End Cell. In which case, NO amount of Ventilation would solve that problem.
You could pump %100 pure oxygen into the lungs with a Ventilator and it would not matter because the hemoglobin that is tasked with picking up that oxygen and transporting it to the cells is simply not there. It would be like donating a million surgical masks to an Amazon warehouse, but then that warehouse has no trucks with which to deliver them.
I'm not saying that I know for a fact that this is how COVID works, I'm only theorycrafting and saying that IF COVID attacks hemoglobin, then this is how it kills.
-----
That being said I've also heard other anecdotal stories. A nurse I know at one of my most frequented ERs says that most people are dying of flash pulmonary edema. In other words, their lungs fill up with fluid so fast that it kills them. She says the only chance these people have is if they are ALREADY intubated and ventilated and under ICU observation when the flash pulmonary edema occurs. That if it were to happen to you in the home, and you called 911, it would already be too late.
This suggests that the virus is attacking lung tissue cells and that was what I originally thought I knew about it.
-----
I dunno. Maybe it attacks lung tissue cells, maybe it attacks hemoglobin. Maybe, for fucks sake, it does both. It is interesting to think, however, that Ventilation in both cases would not be the exact solution and it would rather be the ability of the body to Respirate rather than to Ventilate that would be the killing blow.
This seems to also match up to the reports (non-official as they are) from the EMTs coming back from New York who talk about people who are alert and walking around and breathing heavily, but who still drop dead. The fact that they are walking around and breathing heavily means that they are successfully Ventilating, but perhaps are failing, at a cellular level, to Respirate.
- 1
Sanrith Descartes
Veteran of a thousand threadban wars
- 41,488
- 107,544
You know what I think. I think this is that Zul'Gurub poison some asshole brought back to the bazaar in Wuhan on his dismissed pet bat. That's what I think.
- 2
- 17,781
- 25,896
Vanessa
Uncle Tanya
- 7,689
- 1,417
I'm glad you're well AG; I was thinking about you recently and was worried when you weren't posting as frequently as you usually do.
(Disclaimer: I haven't read this entire thread, I'm really sorry if these vids are reposts)
These two videos really stood out amongst the swath of information videos out there:
Stay safe out there!
(Disclaimer: I haven't read this entire thread, I'm really sorry if these vids are reposts)
These two videos really stood out amongst the swath of information videos out there:
Stay safe out there!
- 17,781
- 25,896
I've already seen the first video and it describes the generally understood pathway of how most viruses work. They hijack a cell and command it to replicate the virus. Yes. But that doesn't mean that he knows exactly how COVID works. I commend him for trying to explain it, but I think he's a bit premature.
That second video... maybe I will watch it tomorrow when I have more time. But in the first 20 seconds the guy makes like 9 different appeals to authority and that really makes me want to puke. Every Hospitalist Doctor on Earth will tell you that Surgeons are not the same thing as them. Surgeons are awesome people and they know a lot of things and are very skilled, to be sure, but they are Mechanics not Medical Doctors.
Don't give me titles and degrees and awards and past achievements, give me actual real and present objective knowledge. You uppity self-conscious little fuck.
I suspect he will be regurgitating the same basic evolutionary viral pathways as Kurtzengatz does. When someone goes through that much trouble to show you how big his dick is in only the first 20 seconds..... well.... color me skeptical.
That second video... maybe I will watch it tomorrow when I have more time. But in the first 20 seconds the guy makes like 9 different appeals to authority and that really makes me want to puke. Every Hospitalist Doctor on Earth will tell you that Surgeons are not the same thing as them. Surgeons are awesome people and they know a lot of things and are very skilled, to be sure, but they are Mechanics not Medical Doctors.
Don't give me titles and degrees and awards and past achievements, give me actual real and present objective knowledge. You uppity self-conscious little fuck.
I suspect he will be regurgitating the same basic evolutionary viral pathways as Kurtzengatz does. When someone goes through that much trouble to show you how big his dick is in only the first 20 seconds..... well.... color me skeptical.
Izo
Tranny Chaser
- 18,521
- 21,369
No, it’s a mix of both. Here, let me quote LITFL:
https://litfl.com/prone-position-and-mechanical-ventilation/ said:
Burren
Ahn'Qiraj Raider
- 4,052
- 5,341
I don't understand this. You're at once stating it's completely true and completely false at the same time?
Also: NYC is indeed a shit hole, regardless of WTF is going on in the world.