Still nowhere close to playing the game for you though, it's literally just telling you which skills are better than others while leveling. You can take the time to test them out once you unlock Trixion but until then it's annoying when you use a 20secs skill and have to wait to change the tripods, and then you have to retest everytime you unlock new tiers.
And ultimately, the guides mostly boil down to "put +range on your movement skills, max the strong aoe skills and give them aoe increasing tripods".
Since I played my class during beta I already know what I'm doing and I don't like what the guide says (too much specing out of movement skill for pitiful damage increases on skills that will one shot trash mobs regardless, when 80% of the time you waste while leveling is moving around) but for people who have no idea, it saves some time on experimenting if they just want to rush to cap. It makes very little difference though as you could do the MSQ by just using autoattacks if you wanted seeing as how easy the game is anyway.