it means you have nothing. no prospects for the future. nothing that can be taken away from you. nothing you care about. except revenge. its basically Drax's story arch in GoTG1 and how far did that get him?
The whole movie just exists so next time Captain Feminism can say, "Hey guize, let's just chop his arm off !" while all the men look at each other and agree womyn should be running things because they're stronger and smarter.
Except Thanos still has it (the gauntlet might have burned, but he didn't leave all those gems littered around).
Expectations are that they use Quantum Realm shenanigans from Ant-man's portals to do so (apparently, Quantum Realm has weird time aspects). Probably tweaked by Tony (when he and Nebula have finished repairing the ship or whatever and reached Earth) and powered by Capt. Marvel.