Anyone with 5+ points into The Pit tree want to test something?
First, have the tree setup so you're using the 4 points necessary to activate Choron's Flesh (middle tree). Make a run, see if it spawns (will be a pedestal near the Glyph thing). While having at least 1 glyph upgrade point remaining, use Choron's Flesh (if it spawned). See if it uses the Glyph currency OR if it used Artificer's Stones.
Second, with Choron's Flesh still active, use a point to activate Choron's Wager. Check your currency for how many Artificers Stones you have. Do a run, see if Choron's Wager spawns during the run, it will be a pedestal similar to the Horadric pedestal thing that takes you to that Horadric Vault place. If it spawns, use it to get the Challenge. If you succeed, check the Artificers Stone amount you now have. Also, after defeating the Guardian, see IF the Choron's Flesh spawns.
For me, the Choron's Flesh hasn't spawned since I activated Choron's Wager. My Wager for the one run its spawned so far was to kill 100 mobs without using a potion. I never got a notice saying I completed it, but I didn't check how many stones I had before or after. Also, the tooltip for Choron's Flesh is apparently wrong; it says using the Flesh will cost 1 of your Glyph upgrade attempts, but it doesn't. It just uses Artificers Stones, as long as you have at least 1 Glyph upgrade available.