Some of the already built in fast travel features are useful to cut down on travel time. For example if you Queue one of the Guk Raids, instead of running you can use the Bazaar port AA and use the map to get to the DZ, only works for the raids. Another trick is instead of Running Butcher -> Gfay-> all the way across LFay. Go Butcher -> TP to the Baz and take the Map to Mistmoore.
I hate that they added Monsters Missions, they're really out of place on this mod.