Just imagine, you are spawned in a Nuclear wasteland random location, say a map the size of fall out new Vegas.
You start with a baseline melee weapon and a couple survivable items such as maybe a health pack and a random potion to buff your run speed, agi, STR or whatever.
There are say, 49 other players on that same map, every player starts in a random location at least 4km in game map size from another player on spawn.
Clock starts on a 30 min match. There are consumables, ammo, health restoration items and other random crafting based items scattered throughout the map randomly. You can then choose to go to a NPC mob spawn and risk killing them to get some loot they are guarding or you could just look for mats to build a defensive outpost.
Or you could run and gun and try to surprise another player by rushing his position and compromising his set up and now take over his items and fortifications via risk taking.
Or you can camp at the edge of the map like a pussy while losing out on valuable resources and items available at different map hot spots.
Either last man or team standing wins, can use radiation haze to shrink the map, can use random NPC rare mob spawns to fuck shit up and throw a wrench into a hot spot, which drops legendary weapons or armor.
That would be FUCKING AMAZING.
Edit: I mean think about it, they could even take it to the next level and allow the player to choose a faction, say Brotherhood of Steel which spawns you at a certain location that has specific benefits and has special ability/weapon unlocks based on the faction you picked. Like SuperMutants start near a swamp that has a ton of a special plant resource that allows buff potions to be made and have access to certain abilities like radiation resist, super STR etc, whereas a human minuteman starting character has access to a settlement that can heal them and they get an ability to track targets on the map for a limited time or something. The possibilities are endless.