What would you say the general progression of mob difficulty is via the Map? East > North > West > South? After defeating the first Boss (wheelchair Karen), I teleported to the Ruins of Mammon (South region), and the mobs there felt noticeably more tanky, but all the Shells and Weapons I want are down there, haha.
Just did the 2nd Boss, lvl19 with a +10 Battle Axe and +6 Crossbow. Debating on going down South again, or heading to the West.