Science!! Fucking magnets, how do they work?

Silicon chip can mediate stem cell production in skin cells to regrow organs within the body.


COLUMBUS, Ohio – Researchers at The Ohio State University Wexner Medical Center and Ohio State’s College of Engineering have developed a new technology, Tissue Nanotransfection (TNT), that can generate any cell type of interest for treatment within the patient’s own body. This technology may be used to repair injured tissue or restore function of aging tissue, including organs, blood vessels and nerve cells.

Results of the regenerative medicine study published today in the journal Nature Nanotechnology.

“By using our novel nanochip technology, injured or compromised organs can be replaced. We have shown that skin is a fertile land where we can grow the elements of any organ that is declining,” said Dr. Chandan Sen, director of Ohio State’s Center for Regenerative Medicine & Cell Based Therapies, who co-led the study with L. James Lee, professor of chemical and biomolecular engineering with Ohio State’s College of Engineering in collaboration with Ohio State’s Nanoscale Science and Engineering Center.

Researchers studied mice and pigs in these experiments. In the study, researchers were able to reprogram skin cells to become vascular cells in badly injured legs that lacked blood flow. Within one week, active blood vessels appeared in the injured leg, and by the second week, the leg was saved. In lab tests, this technology was also shown to reprogram skin cells in the live body into nerve cells that were injected into brain-injured mice to help them recover from stroke.

Posting because unlike post of these pop science claims, this is actually from a study posted in nature, and it appears to be working on mice to save limbs with a 98% success rate. Looks like it's fast tracked for human trials, to begin next year. Can't even imagine a world where a doctor can simply inject a microchip, and regrow tissue, or entire organs.

Lithose said:

Silicon chip can mediate stem cell production in skin cells to regrow organs within the body.


COLUMBUS, Ohio – Researchers at The Ohio State University Wexner Medical Center and Ohio State’s College of Engineering have developed a new technology, Tissue Nanotransfection (TNT), that can generate any cell type of interest for treatment within the patient’s own body. This technology may be used to repair injured tissue or restore function of aging tissue, including organs, blood vessels and nerve cells.

Results of the regenerative medicine study published today in the journal Nature Nanotechnology.

“By using our novel nanochip technology, injured or compromised organs can be replaced. We have shown that skin is a fertile land where we can grow the elements of any organ that is declining,” said Dr. Chandan Sen, director of Ohio State’s Center for Regenerative Medicine & Cell Based Therapies, who co-led the study with L. James Lee, professor of chemical and biomolecular engineering with Ohio State’s College of Engineering in collaboration with Ohio State’s Nanoscale Science and Engineering Center.

Researchers studied mice and pigs in these experiments. In the study, researchers were able to reprogram skin cells to become vascular cells in badly injured legs that lacked blood flow. Within one week, active blood vessels appeared in the injured leg, and by the second week, the leg was saved. In lab tests, this technology was also shown to reprogram skin cells in the live body into nerve cells that were injected into brain-injured mice to help them recover from stroke.

Posting because unlike post of these pop science claims, this is actually from a study posted in nature, and it appears to be working on mice to save limbs with a 98% success rate. Looks like it's fast tracked for human trials, to begin next year. Can't even imagine a world where a doctor can simply inject a microchip, and regrow tissue, or entire organs.

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This sounds awesome but it seems to only work for skin cells, I'm not sure how they could repair an organ with it. Unless there is some aspect of stem cells where no matter where they're generated in the body they will gravitate to the organ where they belong automatically. It's insane stuff for sure.

Lots of other cool shit this week too:
Potential reversal of Alzheimer symptoms: https://medicalxpress.com/news/2017-08-blocking-enzyme-linked-alzheimer-reverse.html
Another similar one for ALS+Dementia: https://medicalxpress.com/news/2017...neration-associated-protein-clumping-lab.html
Heart Regeneration: https://medicalxpress.com/news/2017-08-heart.html
Proven in mice, unproven in humans but they've increased the neuroplasticity of mice which allows them to recover from things like brain injuries etc:
[URL='https://medicalxpress.com/news/2017-08-heart.html']https://medicalxpress.com/news/2017-08-scientists-youthful-plasticity-brains-adult.html
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https://images.nature.com/full/natu...al/vaop/ncurrent/extref/nnano.2017.134-s1.pdf

Here's the Supplementary Information that Nature published. If I'm gathering right, they zap your skin, harvest the area and let it mutate and then inject the mutated cells into where ever they need to go.

Maybe I'm a simpleton but that legitimately blows my mind. Goddamn it that would have been sooooo much easier than years worth of fertility treatments!

All of these crazy medical treatments I've given up on until I see they're available domestically. Too many "the end is nigh for cancer!" "New male birth control being tested!" "inexpensive skin treatment for burn victims!" And a decade later still have never heard of them commercially.

Tuco said:

Does that mean the robot that manufactures these things has to pay child support?

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No but you do after she gets her hands on these things even after you've been snipped and wear a condom. Happy shotgun marriage!

Drakurii said:

3,700-year-old Babylonian tablet rewrites the history of maths - and shows the Greeks did not develop trigonometry

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It's pretty neat that they found evidence of trig being practiced earlier than previously known, and if the base 60 system and other novel methods employed are more accurate than what was used for the next several thousand years, that's pretty fucking cool too. But a couple of the quotes from Dr Mansfield set off my bullshit detector. Both the unit circle and angles are absolutely based on ratios, period. Also, saying that the tablet is the "only completely accurate trigonometric table" is 100% a red herring because the only way to be "completely accurate" is to only include rational numbers in the table, which is another way of saying that the table is omitting an infinite number of absolutely correct irrational numbers. They have a genuinely fascinating historic artifact but the guy describing it in that article appears to be wildly overstating the significance. Maybe there really is something special about the elegant simplicity of the methods? Maybe it's easier to understand and to teach? I'd like to hear more about it, but from someone else's mouth.