Depression

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Ossoi

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I haven't seen much about long-term side effects. I'll do some research on that. My doctor made them sound pretty safe. Only thing I noticed was that I was a little twitchy when I first got on them and it felt like I had a condom on when I was having sex. Thankfully that went away.

I was on Zoloft because I thought I was depressed but was actually miserable at work

The first two weeks on it I had to take off work. Woke up one morning and it was as if someone had dialed the anxiety up to 11. As soon as I opened my eyes I could feel it. Leveled a hunter alt to 60 in the second week, didn't get out of bed for the first lol
 

Cad

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I haven't seen much about long-term side effects. I'll do some research on that. My doctor made them sound pretty safe. Only thing I noticed was that I was a little twitchy when I first got on them and it felt like I had a condom on when I was having sex. Thankfully that went away.

Not everyone will get every side effect, but on Reddit the number of people with SSRI-induced ED, or SSRI induced libido death, or can't orgasm.

The other ones I hear a lot are emotional numbness and weight gain.
 
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Cutlery

Kill All the White People
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Not sure what this means. I haven't been diagnosed with depression, but I did have a random panic attack a couple of years ago, which led into a period vague anxiety/dread. It was really strange how it came out of nowhere but the doc put me on an SSRI, which reduced those symptoms that had arisen. It also seemed to reduce irritability and a produced a drop in BP.

Anyway, reading this, now I am wondering if getting off the pills is something I should discuss with the doc. He said he'd work with me to stop them if and when I ever wanted but preferably not going into or in the middle of Winter. Just one article about one study but something to keep an eye on. I know there can be a relationship between depression and GAD.


I read that article. And then I read this one.


Now I think I'm depressed!
 

Oblio

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Not everyone will get every side effect, but on Reddit the number of people with SSRI-induced ED, or SSRI induced libido death, or can't orgasm.

The other ones I hear a lot are emotional numbness and weight gain.
Yep, that was my experience. Numb to the world and it was hard to reach climax. I fucking hated it, I hated it so much that it was probably the catalyst for to seek help from a therapist. Living that was was not living, at least for me.
 

Cad

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Yep, that was my experience. Numb to the world and it was hard to reach climax. I fucking hated it, I hated it so much that it was probably the catalyst for to seek help from a therapist. Living that was was not living, at least for me.
I had a friend like that, he couldn't really have sex but he said his mood was improved. I was like, if you can't have sex how can your mood be better? I'd want to fucking hang myself just from that. Maybe if you get off that shit and slay some pussy you'll feel better.

Some people don't have those side effects, but it seems like the longer you take it the more likely it is to happen.
 

Oblio

Utah
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I had a friend like that, he couldn't really have sex but he said his mood was improved. I was like, if you can't have sex how can your mood be better? I'd want to fucking hang myself just from that. Maybe if you get off that shit and slay some pussy you'll feel better.

Some people don't have those side effects, but it seems like the longer you take it the more likely it is to happen.
It was a real rough patch in my life so I don't recall the amount of time I was on them, but I think it was less than 6 months. I was really ignorant about the right way to get off of them, I quit cold turkey...DO NOT RECOMMEND!!!! It was horrible, I got worse before I got better. Probably one of the lowest points in my life and I vividly recall having a panic attack the night before I was supposed to fly with my wife to her home town to see her family. Never had a a panic before or sense, it was not fun. I was sitting at the top of the stairs and my heart was pounding as if a fire squad was lined up across from me. My wife was awesome and supportive and told me to stay home. She called me probably every two hours that trip to make sure I was okay.
 
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MusicForFish

Ultra Maga Instinct
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Lol
new york comedy GIF by HULU

 
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Oblio

Utah
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As I mentioned I am thinking about taking some T, I spoke with my Doc about it a few weeks ago. What I really want to do though is look into micro dosing psilocybin or taking a therapeutic does of it or ibogaine or ayahuasca. I asked my Doc about the micro dosing and she had no clue where to refer me or if it was even a thing available. The reason I want to is I hear stories all the time about people that have PTSD from Trauma from War or Abuse and they take some of the good stuff and they are reborn. Sounds like a fairy tale I know, but fuck I want to try. Worst that happens is I have a bad trip, okay I will take that gamble. Anyway this segment linked below gives me hope this might be come a thing that is more available to the masses.

 
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Kyougou

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I haven't seen much about long-term side effects. I'll do some research on that. My doctor made them sound pretty safe. Only thing I noticed was that I was a little twitchy when I first got on them and it felt like I had a condom on when I was having sex. Thankfully that went away.
Is it not odd that you got an anxiety/panic attack and you were given anti depressants?
From my understanding some do a lot of work for similar symptoms, but it still sounds odd if there were no signs of depression?
I dunno, just saying.
 

Kyougou

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I had a friend like that, he couldn't really have sex but he said his mood was improved. I was like, if you can't have sex how can your mood be better? I'd want to fucking hang myself just from that. Maybe if you get off that shit and slay some pussy you'll feel better.

Some people don't have those side effects, but it seems like the longer you take it the more likely it is to happen.
You can definitely have a better mood and no sex drive while on some drugs. Can't really understand it unless you are on them, I guess.
 
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ToeMissile

Pronouns: zie/zhem/zer
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As I mentioned I am thinking about taking some T, I spoke with my Doc about it a few weeks ago. What I really want to do though is look into micro dosing psilocybin or taking a therapeutic does of it or ibogaine or ayahuasca. I asked my Doc about the micro dosing and she had no clue where to refer me or if it was even a thing available. The reason I want to is I hear stories all the time about people that have PTSD from Trauma from War or Abuse and they take some of the good stuff and they are reborn. Sounds like a fairy tale I know, but fuck I want to try. Worst that happens is I have a bad trip, okay I will take that gamble. Anyway this segment linked below gives me hope this might be come a thing that is more available to the masses.

Not a fairy tale at all.

I think ketamine is the only thing available outside of trials/studies, but MDMA just finished up some phase 3 trials for PTSD run by MAPS MDMA - Multidisciplinary Association for Psychedelic Studies - MAPS

The study is on the small side, but very promising.
The new study—a phase III clinical trial—involved 91 patients across 15 sites who were randomized to receive either MDMA (3,4-methylenedioxy-methamphetamine) or a placebo. Neither the participants nor the researchers knew who had been given the psychoactive drug. The scientists found that 67 percent of PTSD sufferers who had MDMA with an intensive course of psychotherapy no longer qualified for a PTSD diagnosis following the trial, compared with 32 percent of those who received a placebo with psychotherapy. And 88 percent of subjects in the MDMA group experienced a “clinically significant improvement” in symptoms.

Johns Hopkins has been doing serious research for close to a decade I think: Center for Psychedelic & Consciousness Research

Huberman Lab podcast always has top notch info with direct links to studies mentioned

 

Break

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I have a friend who is depressed, and I really have no idea how to help her. It seems like everything in life sends her on a spiral of self doubt and self hatred. Like something happens with her kid that has absolutely nothing to do with her... oh my god I'm a bad mom, my kids hate me, they would be better off with someone else... etc. She worked over at my house one day just because me and my wife are always home and she didn't want to be alone, like emails from her boss that were even slightly criticizing would send her into a 2 hour tailspin trying to decide if she's going to be fired. She seems like she's just constantly anxious about everything, even shit that nobody can do anything about (like what if my flight is cancelled? That would be just my luck! We should go home by midnight because the drunks are out later, with my luck we will all be killed... )

So.. what the fuck does a friend do in this situation? Telling her it's all in her head doesn't seem to help. Telling her she's actually a fantastic person doesn't help. She has a lot of friends and people who care about her, but she thinks she's dead-weight on all of them and is generally spiraling out of control. Financially she is well off, she's good looking, reasonably young, and is educated and has a good job. There's nothing objectively wrong with her or her life, other than this attitude.

What can be done from the outside to help? Do you just encourage and give opportunities and then pull back and put it on her? I have tried dragging her by the neck to events to have fun and she seems to generally have fun, but then will be "exhausted" for days after and be right back to the same thing.

What do?
Sounds like "high trait neuroticism", if you can suggest she takes Jordan Peterson's big 5 test and maybe self-authoring, especially past-authoring.
 

Hatorade

A nice asshole.
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Not going to say I solved depression but it only hits me rarely now instead of daily.

For those still struggling on the regular. Do something that feels dangerous, it really focuses you down to only what you are doing. Sure ignoring the problem won’t solve it but if you know it is just a chemical thing introduce more better chemicals.

This is working for me, went from riding mountain bikes around tame trails to blasting down mountains, then onto BMX with larger and larger jumps. Hell even when I would chicken out the rush of rolling up to a big ass lip would be enough.

I am now trying to get good at motorcross, jumps are easy but cornering is taking a ton of practice. Scaring yourself with a throttle twist is good stuff, and hard to beat the feeling on clearing a big ass jump for the first time because you got the corner before it right.

This can be anything you want to do, just pick something that physically puts you out there. Added benefit of exercise is always good.
My 2 cents.
 
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moonarchia

The Scientific Shitlord
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Not going to say I solved depression but it only hits me rarely now instead of daily.

For those still struggling on the regular. Do something dangerous, it really focuses you down to only what you are doing. Sure ignoring the problem won’t solve it but if you know it is just a chemical thing introduce more better chemicals.

This is working for me, went from riding mountain bikes around tame trails to blasting down mountains, then onto BMX with larger and larger jumps. Hell even when I would chicken out the rush of rolling up to a big ass lip would be enough.

I am now trying to get good at motorcross, jumps are easy but cornering is taking a ton of practice. Scaring yourself with a throttle twist is good stuff, and hard to beat the feeling on clearing a big ass jump for the first time because you got the corner before it right.

This can be anything you want to do, just pick something that physically puts you out there. Added benefit of exercise is always good.
My 2 cents.
Skip the dangerous part, but definitely can second the physical activity part. Getting your body moving gets the endorphins flowing.
 

Hatorade

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Skip the dangerous part, but definitely can second the physical activity part. Getting your body moving gets the endorphins flowing.
You know how hard it is to exercise when depressed? Fuck that, consistently go do something you find fun that just happens to get you moving, calculated danger got me out there on the daily.
Finding that thing can also be difficult, I suggested bike stuff because most cities have skate parks, most rural areas have motocross tracks or at least somewhere to ride.
Not everything is like OMG I’m gonna die either, you get good at pump tracks and they are way more fun then scary.
If I lived somewhere with scenic hikes I would find the tallest one, if I lived near a lake I would jet ski etc.
You also get to wrench on the stuff you ride adding to sense of accomplishment which also helps.
 
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moonarchia

The Scientific Shitlord
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You know how hard it is to exercise when depressed? Fuck that, consistently go do something you find fun that just happens to get you moving, calculated danger got me out there on the daily.
Finding that thing can also be difficult, I suggested bike stuff because most cities have skate parks, most rural areas have motocross tracks or at least somewhere to ride.
Not everything is like OMG I’m gonna die either, you get good at pump tracks and they are way more fun then scary.
If I lived somewhere with scenic hikes I would find the tallest one, if I lived near a lake I would jet ski etc.
You also get to wrench on the stuff you ride adding to sense of accomplishment which also helps.
Hello mentally unstable person, have you ever thought about incorporating death defying stunts into your life? .... what could possibly go wrong?

Pretty sure I would only even think about seriously suggesting that to someone who is depressed if they were about to 41% themself. And if they were stupid I might suggest going ahead with the 41% instead of risking them taking others out with them.

And having spent 15 years as a manic depressive, I do remember how hard it is to motivate yourself when you are down. But if you have found the motivation to do something, you are going to get better results in the long run doing something positive rather than going from one extreme to another.
 

Hatorade

A nice asshole.
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Hello mentally unstable person, have you ever thought about incorporating death defying stunts into your life? .... what could possibly go wrong?

Pretty sure I would only even think about seriously suggesting that to someone who is depressed if they were about to 41% themself. And if they were stupid I might suggest going ahead with the 41% instead of risking them taking others out with them.

And having spent 15 years as a manic depressive, I do remember how hard it is to motivate yourself when you are down. But if you have found the motivation to do something, you are going to get better results in the long run doing something positive rather than going from one extreme to another.
I agree and I should have put a qualifier on the dangerous part(edit made) but no where did I say death defying, when I first started small roll ins were challenging and a little scary. Going 10 MPH into a tall berm was a little scary, rolling anything made of wood etc.

So I will say do something new that challengers you physically, it focuses the mind.
 
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Borzak

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I've asked for anti depressants over and over from multiple doctors and specialist. I have no idea why I am depressed. Can't drive, can't work, can't walk at times, need to drink through a straw at times. Nothing.

I've been given tramadol, hydrocodine, oxycodine, oxycontin. No anti depressants. Finally yesterday a doctor can't straight give you anti depressants without you going through a flowchart checklist. Corporate BS has taken the ability of doctors to make a decision apparently. Dr. said Okay but I have to fill out this questionaire first to have it all recorded. He did not like at all when I told him the majority of my depression comes from dealing with BS like this and not my medical issues.

Ever feel like hurting yourself? Nope, doctors at times yes.
 

Falstaff

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Just sign up for cerebral and tell them your symptoms and you’ll get anti depressants in like 5 minutes.
 

Razzes

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I've asked for anti depressants over and over from multiple doctors and specialist. I have no idea why I am depressed. Can't drive, can't work, can't walk at times, need to drink through a straw at times. Nothing.

I've been given tramadol, hydrocodine, oxycodine, oxycontin. No anti depressants. Finally yesterday a doctor can't straight give you anti depressants without you going through a flowchart checklist. Corporate BS has taken the ability of doctors to make a decision apparently. Dr. said Okay but I have to fill out this questionaire first to have it all recorded. He did not like at all when I told him the majority of my depression comes from dealing with BS like this and not my medical issues.

Ever feel like hurting yourself? Nope, doctors at times yes.
That is weird, SSRI are like the easiest med to get. I'm not sure how useful they are for pure depression though. From what I understand, SSRI works better on depression that stems from chronic anxiety (or I guess if your depressed state causes you anxiety), which happens alot. By numbing you a bit, they allow you to chill and enjoy again what you used to.